A examine revealed earlier this month within the scientific journal Cosmetics by researchers from Thailand has concluded that extracts from the Dendrobium sulcatum Lindl Orchid plant are “a promising supply of pure energetic elements for anti-skin-aging.” Researchers examined “the organic actions, together with antioxidation, anti-lipid peroxidation, antiglycation, anti-inflammatory and anti-tyrosinase properties of ethanolic extract of D. sulcatum stems, leaves and flowers, which had been efficiently elucidated and revealed for the primary time.”
Research background and objectives
Thailand is without doubt one of the largest Orchid rising areas globally. As detailed within the examine, Dendrobium species particularly have been used traditionally in Chinese language folks drugs for his or her anti-inflammatory properties, and just lately, “beauty and cosmeceutical purposes of the Orchidaceae household and a few Dendrobium species have been reported to be doubtlessly energetic in reducing melanin manufacturing, antioxidation, anti-aging with MMP2 inhibitory impact and tyrosinase inhibition. Nonetheless, till researchers carried out this examine, the potential advantages of Dendrobium sulcatum in topical beauty purposes remained unexplored.
The analysis workforce sought to first derive and decide the phytochemical make-up of Dendrobium sulcatum extracts earlier than investigating the potential anti-aging advantages, together with the extract’s doable antioxidant, antiglycation, anti-inflammatory, and anti-tyrosinase properties. To start the examine, researchers harvested a complete plant specimen from Muang, Nan Province, Thailand. They first separated the stem, leaves, and flowers then cleaned and dried every. The plant matter was then floor right into a wonderful powder, extracted with ethanol, and filtered right into a crude extract for testing and evaluation.
Testing flavonoid and phenolic content material
“The flavonoid and phenolic compounds are referred to as plant secondary metabolites for antioxidation, anti-inflammation, and many others., which could be associated to the standard use of this plant as a well being tonic and anti-aging remedy,” researchers reported. “Subsequently, the content material of flavonoids and phenols was characterised on this examine.”
Testing to look at complete phenolic and flavonoid contents had been carried out first, using gallic acid and quercetin, respectively. The outcomes of phenolic contents decided that “the stem and leaf extracts had the next content material of complete phenolic contents than the flower extract, which indicated that each one ethanolic extracts of D. sulcatum comprise phenolic compounds.”
Flavonoid content material testing additionally utilized the ethanolic extract of the stems, leaves, and flowers of D. sulcatum, and “outcomes confirmed that the very best worth of complete flavonoid content material was obtained from the leaf extract adopted by the flower and stem extracts.” Outcomes revealed that the “flavonoid constituents present in Dendrobium species had been flavone C-glycosides and flavonols.”
Figuring out antioxidant and anti inflammatory potential
Following these assessments, “the three totally different components of D. sulcatum, specifically stem, leaf and flower extracts had been investigated for antioxidant properties utilizing DPPH radical scavenging exercise, ferric decreasing antioxidant energy (FRAP) and ABTS radical scavenging assays.”
The first antioxidant screening utilized DPPH free radical scavenging assay, and “among the many check samples, the one exhibiting the very best antioxidant impact was the leaf extract, which was about 1.5 and three occasions larger than stem and flower extracts, respectively. These outcomes counsel that the ethanolic extract of D. sulcatum leaves has better potential for DPPH free radical scavenging than the opposite components.”
Extra testing using the FRAP and ABTS radical scavenging assays confirmed “larger antioxidant actions within the ethanolic extracts of the leaves and stems than in these of the flower extracts, and that the leaf extract tends to be extra energetic in antioxidation than extracts of different components.”
General conclusions
Primarily based on the outcomes of the in depth testing carried out, researchers concluded that there’s sturdy scientific proof supporting Dendrobium sulcatum’s efficacy as an anti-inflammatory, anti-aging bioactive ingredient in topical beauty merchandise. Take a look at outcomes point out that extracts from the stems and leaves present extra vital potential advantages than the Orchid plant’s flowers.
Researchers additionally famous that “the limitation of this examine is that the foremost chemical constituents related to the organic actions of D. sulcatum extracts should not recognized,” as this examine was the primary of its sort. Subsequently, “additional research to establish the biomarkers, consider the cytotoxicity of human cells, and carry out high quality management and pre-formulation examine of the plant extracts can be important for additional software of the extracts in beauty and cosmeceutical merchandise.”
Supply: Cosmetics
2023; 10(2):43. https://doi.org/10.3390/cosmetics10020043
“Evaluation of Antioxidant, Anti-Lipid Peroxidation, Antiglycation, Anti-Inflammatory and Anti-Tyrosinase Properties of Dendrobium sulcatum Lindl”
Authors: Rungsang T., et al